Morgane Deffense was born and raised in Brussels. She discovered ceramics during her studies at the La Cambre higher school in Brussels.
At the end of her training in 2009, she began to teach in several Academies of Fine Arts in Belgium. In 2012, during an artist residency in the United Kingdom, she decided to settle in Scotland where she will link experiences and meetings. One of them is its collaboration with the Project Ability art center, which targets an audience with disabilities. These life experiences will influence and mark his work.
Since 2017, Morgane Deffense has been a professor of the ceramic option at plateau 96 with the ArtsCade and Indigo group as well as at the Académie des Beaux-Arts de Châtelet.